Dr. Anna Grandchamp


Postdoctoral Research Associate




Email: a.grandchamp@wwu.de

Tel.: +49-(0)251-83-21636

Room: 100.22

Scientific Career and Education

  • Ongoing: present Postdoctoral Researcher in the DFG funded SPP 2349 GEvol: Genomic Basis of Evolutionary Innovationsat the Institute for Evolution and Biodiversity, University of Münster
  • 2020-2022: Humboldt fellowship for Post-doc at the Institute for Evolution and Biodiversity, University of Münster
  • 2019-2020: Post-doc at the Institute for Evolution and Biodiversity, University of Münster
  • 2015 - 2018: PhD in evolution and bioinformatics, diploma in bioinformatics (CNAM)
  • 2013 - 2015: MA research in Biology Ecology and Evolution
  • 2010 - 2013: Bachelor in Biology

Research Interests

  • Evolution of ligands and receptors in animal phylogeny
  • De novo genes emergence
  • Genomes evolution

Publications

  • Lebherz Marie Kristin, Fouks Bertrand, Schmidt Julian, Bornberg-Bauer Erich and Grandchamp Anna. "DNA Transposons favour de novo transcript emergence through enrichment of transcription factor binding motifs." bioRxiv (2023): 2023-10.
  • Ravi Iyengar Bharat, Grandchamp Anna, and Erich Bornberg-Bauer. "How antisense transcripts can evolve to encode novel proteins." bioRxiv (2023): 2023-09.
  • Grandchamp, Anna, Peter Czuppon, and Erich Bornberg-Bauer. "Quantification and modeling of turnover dynamics of de novo transcripts in Drosophila melanogaster." bioRxiv (2023): 2023-02. Accepted in NAR
  • Grandchamp, Anna, Lucas Kühl, Marie Kristin Lebherz, Kathrin Brüggemann, John Parsch, and Erich Bornberg-Bauer. "Population genomics reveals mechanisms and dynamics of de novo proto-gene emergence in Drosophila melanogaster." Genome Research vol 33; no. 6 (2023).
  • Grandchamp, Anna, Katrin Berk, Elias Dohmen, and Erich Bornberg-Bauer. "New genomic signals underlying the emergence of human proto-genes." Genes 13, no. 2 (2022): 284.
  • Rivard, Emily L., Andrew G. Ludwig, Prajal H. Patel, Anna Grandchamp, Sarah E. Arnold, Alina Berger, Emilie M. Scott et al. "A putative de novo evolved gene required for spermatid chromatin condensation in Drosophila melanogaster." PLoS genetics 17, no. 9 (2021): e1009787
  • Picolo, Floriane, Anna Grandchamp, Benoît Piégu, Antoine D. Rolland, Reiner A. Veitia, and Philippe Monget. "Genes encoding teleost orthologs of human haploinsufficient and monoallelically expressed genes remain in duplicate more frequently than the whole genome." International journal of genomics 2021 (2021).
  • Grandchamp, Anna, and Philippe Monget. “The membrane receptors that appeared before their ligand: The different proposed scenarios” Plos one 15.5 (2020)
  • Grandchamp, Anna, and Philippe Monget. “Synchronous Birth Is a Dominant Pattern in Receptor-Ligand Evolution.” BMC Genomics 19, no. 1 (August 14, 2018): 611.
  • Grandchamp, Anna, Benoît Piégu, and Philippe Monget. “Genes Encoding Teleost Fish Ligands and Associated Receptors Remained in Duplicate More Frequently than the Rest of the Genome.” Genome Biology and Evolution 11, no. 5 (May 1, 2019)
  • Grandchamp, Anna, Shifa Tahir, and Philippe Monget. 2019. “Natriuretic Peptides Appeared after Their Receptors in Vertebrates.” BMC Evolutionary Biology 19 (1): 215 (November 2019)